Pipeline

Publications

Journal Date Title Link
Gastroenterology, online 2020 Cadherin 11 Promotes Immunosuppression and Extracellular Matrix Deposition to Support Growth of Pancreatic Tumors and Resistance to Gemcitabine in Mice
Cancer Research 2020 Targeting Glycosylated PD-1 Induces Potent Anti-tumor Immunity
Cancer Cell 2018 Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1
Nature communications 2016 Glycosylation and Stabilization of Programmed Death Ligand-1 Suppresses T-cell Activity
Cancer cell 2016 Targeting Glycosylated PD-1 Induces Potent Anti-tumor Immunity
Clinical Cancer Research 2016 Implications of the Bystander and Abscopal Effects of Radiation Therapy
Journal of Thoracic Oncology 2014 A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non-Small Cell Lung Cancer

Related papers

Journal Date Title Link
Cancer Cell 2019 Removal of N-Linked Glycosylation Enhances PD-L1 Detection and Predicts Anti-PD-1/PD-L1 Therapeutic Efficacy.
Cancer Research 2018 Posttranslational Modifications of PD-L1 and Their Applications in Cancer Therapy.
Molecular Cell 2018 Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1.
Nature Communications 2018 STT3-dependent PD-L1 accumulation on cancer stem cells promotes immune evasion.
American Journal of Cancer Research 2018 Deglycosylation of PD-L1 by 2-deoxyglucose reverses PARP inhibitor-induced immunosuppression in triple-negative breast cancer.
Cancer Cell 2018 Glycans Pave the Way for Immunotherapy in Triple-Negative Breast Cancer.
Front Pharmacology 2018 A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non-Small Cell Lung Cancer
Lung Cancer 2018 Spatial interaction of tumor cells and regulatory T cells correlates with survival in non-small cell lung cancer..